Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas-mediated apoptosis of B and non-B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
55179 |
| Alternate Names |
- FAIM1FLJ10582
- fas apoptotic inhibitory molecule 1
- Fas apoptotic inhibitory molecule
|
Research Areas for FAIM1
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
