Species: Hu, Mu, Rt, Ch
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
5167 |
Alternate Names |
- ectonucleotide pyrophosphatase/phosphodiesterase 1
- E-NPP 1
- Ly-41 antigen
- M6S1NPP1
- Membrane component chromosome 6 surface marker 1
- membrane component, chromosome 6, surface marker 1
- NPPSalkaline phosphodiesterase 1
- PC1
- PC-1
- PCA1ARHR2
- PDNP1ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- Phosphodiesterase I/nucleotide pyrophosphatase 1
- plasma-cell membrane glycoprotein 1
- Plasma-cell membrane glycoprotein PC-1
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Research Areas for ENPP-1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism