EMI1 Products

Description

Fbp5A is a member of the F-box protein family that is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to Xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase-promoting complex.

Bioinformatics

Entrez	26271 Human
Uniprot	NM_012177 Human NP_036309 Human Q9UK58 Human Q9UKT4 Human
Product By Gene ID	26271
Alternate Names	EMI1Early mitotic inhibitor 1 F-box only protein 5 F-box protein 5 FBX5F-box protein Fbx5 Fbxo31