EIF3M Products

Description

"EIF3M component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).

Bioinformatics

Entrez	10480 Human 295975 Rat 98221 Mouse
Uniprot	NM_006360 Human NP_006351.2 Human Q7L2H7 Human
Product By Gene ID	10480
Alternate Names	B5 receptor dendritic cell protein eIF3m eukaryotic translation initiation factor 3 subunit M eukaryotic translation initiation factor 3, subunit M Fetal lung protein B5 FLJ29030 GA17 HFLB5 hFL-B5 hfl-B5 PCI domain containing 1 (herpesvirus entry mediator) PCI domain-containing protein 1 PCID1B5