EED Products

Description

EED encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Bioinformatics

Entrez	8726 Human
Uniprot	NM_003797 Human NM_152991 Human NP_003788 Human NP_003788.2 Human O75530 Human
Product By Gene ID	8726
Alternate Names	embryonic ectoderm development HEED hEED polycomb protein EED WAIT1 WAIT-1 WD protein associating with integrin cytoplasmic tails 1

Related EED Blog Posts

Check out the latest blog posts on EED.

EZH1 has more to offer than gene repression EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...    Read more.

Microglia: pruning shears for homeostatic maintenance in the brain By Jennifer Sokolowski, MD, PhD.Microglia play a critical role in pruning neurons and synapses during homeostatic maintenance in the adult brain.1 A recent study by Ayata et al. (2018) identified regional differe...    Read more.

Read more EED related blogs.