Species: Hu, Mu
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
B cell adapter molecule (BAM32) is also designated a dual adapter for phosphotyrosine and 3-phosphotyrosine, and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC gamma2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
27071 |
Alternate Names |
- B lymphocyte adapter protein Bam32
- BAM32DKFZp667E0716
- B-cell adapter molecule of 32 kDa
- dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
- dual adaptor of phosphotyrosine and 3-phosphoinositides
- hDAPP1
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Research Areas for DAPP1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction