Species: Hu, Ca
Applications: ELISA, Flow, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human Human |
Product By Gene ID |
10217 |
Alternate Names |
- C3orf8
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3
- CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase-like
- CTD small phosphatase-like protein
- CTDSP-like
- EC 3.1.3
- hYA22
- HYA22
- NIF1
- NIFL
- NIF-like protein
- NLI-interacting factor 1
- Nuclear LIM interactor-interacting factor 1
- Protein YA22
- PSR1
- RB protein serine phosphatase from chromosome 3
- RBSP3EC 3.1.3.16
- SCP3chromosome 3 open reading frame 8
- Small CTD phosphatase 3
- Small C-terminal domain phosphatase 3
- YA22
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