Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
COPR5 is a Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that COPR5 acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
55352 |
| Alternate Names |
- C17orf79
- chromosome 17 open reading frame 79
- cooperator of PRMT5
- COPR5
- FLJ21119
- HSA272196
- Protein TTP1
- TTP1
|
