BMP-5 Products

Description

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Bioinformatics

Entrez	12160 Mouse 653 Human
Uniprot	AAH27958 Human AAH27958.1 Human NM_021073 Human NP_066551 Human NP_066551.1 Human P22003 Human
Product By Gene ID	653
Alternate Names	BMP-5 bone morphogenetic protein 5 MGC34244

Research Areas for BMP-5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Cytokine Research