ATP6V1D Products

Description

ATP6V1D encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.

Bioinformatics

Entrez	51382 Human
Uniprot	AAH01411 Human NP_057078 Human Q9Y5K8 Human
Product By Gene ID	51382
Alternate Names	ATP6M ATPase, H+ transporting lysosomal, member M ATPase, H+ transporting, lysosomal (vacuolar proton pump) ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D H(+)-transporting two-sector ATPase, subunit M vacuolar ATP synthase subunit D vacuolar H-ATPase subunit D vacuolar proton pump D subunit vacuolar proton pump delta polypeptide Vacuolar proton pump subunit D vacuolar proton-ATPase subunit D VATDV-ATPase D subunit V-ATPase 28 kDa accessory protein V-ATPase subunit D VMA8 V-type proton ATPase subunit D