ATP6V0D1 Products

Description

ATP6V0D1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.

Bioinformatics

Entrez	9114 Human
Uniprot	AAH08861 Human NM_004691 Human NP_004682 Human P61421 Human
Product By Gene ID	9114
Alternate Names	32 kDa accessory protein ATP6D ATP6DV ATP6V0 ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 FLJ43534 H(+)-transporting two-sector ATPase, subunit D p39 P39 Vacuolar proton pump subunit d 1 V-ATPase 40 kDa accessory protein V-ATPase AC39 subunit V-ATPase, subunit D VATX Vma6 VMA6 VPATPDV-ATPase subunit d 1 V-type proton ATPase subunit d 1