ATP5A Products

Description

ATP5A encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the same protein have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq]

Bioinformatics

Entrez	498 Human
Uniprot	NM_004046 Human NP_001001937.1 Human P25705 Human
Product By Gene ID	498
Alternate Names	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform1, cardiac muscle ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform2, non-cardiac muscle-like 2 ATP sythase (F1-ATPase) alpha subunit ATP5AL2 ATP5AMOM2 ATPMATP synthase subunit alpha, mitochondrial cardiac muscle EC 3.6.3 EC 3.6.3.14 hATP1 mitochondrial ATP synthetase, oligomycin-resistant OMR ORMATP synthase alpha chain, mitochondrial