ATG4C Products

Description

ATG4C is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

Bioinformatics

Entrez	242557 Mouse 313391 Rat 84938 Human
Uniprot	NM_178221 Human NP_116241 Human NP_116241.2 Human NP_835739 Human Q96DT6 Human
Product By Gene ID	84938
Alternate Names	APG4 autophagy 4 homolog C (S. cerevisiae) APG4 autophagy 4 homolog C APG4C ATG4 autophagy related 4 homolog C (S. cerevisiae) AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteineendopeptidase (S. cerevisiae) AUTL1 AUTL3APG4-C AUT-like 1, cysteine endopeptidase AUT-like 3 cysteine endopeptidase Autophagin-3 autophagin-3 Autophagy-related cysteine endopeptidase 3 Autophagy-related protein 4 homolog C cysteine protease ATG4C EC 3.4.22 EC 3.4.22.- FLJ14867

Research Areas for ATG4C

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Phospho-Specific

Related ATG4C Blog Posts

Check out the latest blog posts on ATG4C.

ATG4C - A regulator of the early steps of autophagosome assembly Autophagy is an important cellular process that maintains homeostasis by degrading and recycling damaged proteins and organelles. Autophagy receptors, such as p62/SQSTM1, recognize these intracellular cargo and mediate their engulfment by the doubl...    Read more.

Read more ATG4C related blogs.