alcohol dehydrogenase 5 Products

Description

The ADH5 gene encodes glutathione dependent formaldehyde dehydrogenase or class III alcohol dehydrogenase chi subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, retinol, ethanol and other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class III alcohol dehydrogenase is a homodimer composed of 2 chi subunits. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long chain primary alcohols and for oxidation of S hydroxymethyl glutathione, a spontaneous adduct between formaldehyde and glutathione. The enzyme is an important component of cellular metabolism for the elimination of formaldehyde, which is a potent irritant and sensitizing agent that causes rhinitis, lacrymation, contact dermatitis and pharyngitis.

Bioinformatics

Entrez	11532 Mouse 128 Human
Uniprot	AAH14665 Human NP_000662 Human NP_000662.3 Human P11766 Human
Product By Gene ID	128
Alternate Names	ADH-3 ADHXEC 1.1.1.1 alcohol dehydrogenase (class III), chi polypeptide alcohol dehydrogenase 5 (class III), chi polypeptide Alcohol dehydrogenase 5 Alcohol dehydrogenase class chi chain alcohol dehydrogenase class-3 Alcohol dehydrogenase class-III EC 1.1.1 EC 1.1.1.- EC 1.1.1.284 FALDH FDHGSNOR formaldehyde dehydrogenase Glutathione-dependent formaldehyde dehydrogenase GSH-FDH S-(hydroxymethyl)glutathione dehydrogenase

Research Areas for alcohol dehydrogenase 5

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Core ESC-Like Genes
Stem Cell Markers