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4-1BB Ligand/TNFSF9 Products

Antibodies
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody [Unco...
AF1246
Species: Mu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody [Unco...
AF2295
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
4-1BB Ligand/TNFSF9 Antibody ...
4-1BB Ligand/TNFSF9 Antibody (2357...
MAB22951
Species: Hu
Applications: IHC
Host: Rabbit Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human 4-1BB Ligand/TNFSF9 - ...
Human 4-1BB Ligand/TNFSF9 - Ready...
NBP3-38753
Species: Hu
Applications: ELISA
Human 4-1BB Ligand/TNFSF9 ELI ...
Human 4-1BB Ligand/TNFSF9 ELISA Ki...
NBP3-38754
Species: Hu
Applications: ELISA
Lysates
4-1BB Ligand/TNFSF9 Overexpre ...
4-1BB Ligand/TNFSF9 Overexpression...
NBL1-17171
Species: Hu
Applications: WB
Proteins
Recombinant Mouse 4-1BB Ligan ...
Recombinant Mouse 4-1BB Ligand/TNF...
1246-4L/CF
Species: Mu
Applications: Binding Activity, Bioactivity
Formulation Catalog # Availability Price  
Recombinant Mouse 4-1BB Ligan ...
Recombinant Mouse 4-1BB Ligand/TNF...
1246-4L
Species: Mu
Applications: Binding Activity, Bioactivity
Formulation Catalog # Availability Price  
Recombinant Human 4-1BB Ligan ...
Recombinant Human 4-1BB Ligand/TNF...
2295-4L/CF
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  

Description

CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumor necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen over stimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.

Bioinformatics

Entrez Mouse
Human
Uniprot Human
Human
Human
Mouse
Product By Gene ID 8744
Alternate Names
  • 4-1BB ligand
  • 4-1BBL
  • 4-1BB-L
  • CD137L
  • homolog of mouse 4-1BB-L
  • receptor 4-1BB ligand
  • tumor necrosis factor (ligand) superfamily, member 9
  • tumor necrosis factor ligand superfamily member 9

Research Areas for 4-1BB Ligand/TNFSF9

Find related products by research area and learn more about each of the different research areas below.

Apoptosis