Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Mu
Applications: PAGE
Species: Hu
Applications: AC
Description
15-PGDH (15-hydroxyprostaglandin dehydrogenase (NAD+)) is responsible for prostaglandin inactivation and supports the regulation of functions that are controled by prostaglandin levels. Specifically, 15PGDH catalyzes the chemical reaction to convert NAD+ to NADH and H+.
15-PGDH is a novel tumor suppressor in the COX-2 pathway. 15-PGDH is found in many normal tissues and appears to be down-regulated in colorectal and lung carcinoma tissue.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
3248 |
Alternate Names |
- 15-hydroxyprostaglandin dehydrogenase [NAD+]
- 15-PGDH
- EC 1.1.1
- EC 1.1.1.141
- hydroxyprostaglandin dehydrogenase 15-(NAD)
- NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
- PGDH1PGDH
- Prostaglandin dehydrogenase 1
- SDR36C1
- short chain dehydrogenase/reductase family 36C, member 1
|
Research Areas for 15-PGDH/HPGD
Find related products by research area and learn more about each of the different research areas below.
CancerImmunologyInnate Immunity