SR-B1 belongs to the CD36 scavenger receptor family and serves as a receptor for several ligands including phospholipids, cholesterol ester, lipoproteins, phosphatidylserine, and caveolae localized HDL. It is expressed in endothelial cells, macrophages, and dendritic cells. It facilitates the flux of both free and esterified cholesterol between the cell surface and extracellular donors and acceptors (HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins).
