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ABC transporter family

Understanding Sitosterolemia: How ABCG5-ABCG8 Dimer Affects Blood Sterol Levels

The ATP binding cassette (ABC) transporter family is the largest and most diverse family of membrane transport proteins and, as the name suggests, uses the energy generated by ATP hydrolysis to transport substrates across membranes. Eukaryotic ABC transporters are divided in to full or half transporters, and in to seven sub-families named A through to G (1).