Encoded by the HIF1A gene, HIF-1 alpha has a critical role in cellular response to hypoxia. In hypoxic conditions, HIF-1 alpha activates the transcription of several genes to facilitate metabolic reaction for lack of oxygen. In normoxic conditions, HIF-1 alpha is degraded by the proteasome system.
Learn more about HIF-1 Alpha in our infographic below.
Novus Biologicals offers various HIF-1 alpha reagents for your research needs including:
Resources:
Download the HIF1A infographic.
By: Lisa Ikariyama; Design: Kim Mesman