14-3-3 gamma Products

Description

14-3-3 protein gamma is a member of the 14-3-3 family of proteins which help mediate signal transduction. Specifically, 14-3-3 gamma is an adapter protein responsible for bringing signal transduction to completion. It therefore plays an important role in regulating many fundamental cellular processes, such as apoptosis and cell-cycle checkpoints.

Signal-induced phosphorylation has the ability to change protein function, however phosphorylation is not always enough to change a protein's function. 14-3-3 gamma has the ability to bind a large number of target proteins thereby affecting the proteins' activity and/or function.

14-3-3 gamma is highly expressed in brain, heart and skeletal muscle, where it is induced by growth factors in human vascular smooth muscle cells. This suggests that 14-3-3 gamma may play a role in muscle tissue function.

Bioinformatics

Entrez	22628 Mouse 56010 Rat
Uniprot	AAH20963 Human NM_012479 Human NP_036611 Human NP_036611.2 Human P61981 Human
Product By Gene ID	7532
Alternate Names	14-3-3 gamma 14-3-3 protein gamma 14-3-3GAMMA KCIP-1 Protein kinase C inhibitor protein 1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gammapolypeptide

Research Areas for 14-3-3 gamma

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Growth and Development
Neuronal Cell Markers
Neuroscience
Signal Transduction
Stem Cell Markers