VAMP-1/VAMP-2 Antibody (540524) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

VAMP-1 (vesicle-associated membrane protein 1; also synaptobrevin-1/SYB1) is an 18 kDa member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils and skeletal muscle cells, and participates in vesicle fusion with the plasma membrane. Human VAMP-1 is a type IV transmembrane protein that contains an N-terminal cytoplasmic region (aa 1‑96) and a 22 aa transmembrane domain (aa 97‑118). There is one coiled-coil region between aa 33‑93. Multiple splice variants are known that show two, three, four and 81 aa substitutions for the C-terminal five amino acids. One three aa variant creates a mitochondrial targeting motif. Over aa 1‑96, human VAMP-1 is 98% aa identical to mouse VAMP-1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Steve Stowers	ICC	Drosophila	02/10/2018	View Summary Application Immunocytochemistry Sample Tested Larval neuromuscular junction,Larval ventral nerve cord Species Drosophila Lot CCWM0111801A Comments Comments Antibody recognizes Drosophila homolog of VAMP1/2 (neuronal-synaptobrevin) and gives strong staining.

Array MAB5958

• VAMP-1/VAMP-2 Antibodies