VAMP3/Cellubrevin Antibody

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer's disease, all VAMP isoform levels appear to be significantly reduced.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Canine.

We have publications tested in 2 applications: ICC/IF, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NB300-510	Applications	Species
Fekete CD, Horning RZ, Doron MS, Nishiyama A Cleavage of VAMP2/3 affects oligodendrocyte lineage development in the developing mouse spinal cord The Journal of neuroscience : the official journal of the Society for Neuroscience 2023-08-23 [PMID: 37620160]
Calcagni' A, Staiano L, Zampelli N et al. Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation Nature communications 2023-07-03 [PMID: 37400440] (WB)	WB
L Pan, A Trimarco, AJ Zhang, K Fujimori, Y Urade, LO Sun, C Taveggia, Y Zhang Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination Elife, 2023-02-13;12(0):. 2023-02-13 [PMID: 36779701]
Gu Y, Princely Y, Kumar S et al. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. EMBO J. 2019-10-18 [PMID: 31625181]
Beaton N, Rudigier C, Moest H et al. TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling. Mol Metab 2015-11-01 [PMID: 26629404] (ICC/IF)	ICC/IF
Vogel GF, Klee KM, Janecke AR et al. Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3. J Cell Biol. 2015-11-09 [PMID: 26553929] (WB, Human)	WB	Human
Hager HA, Roberts RJ, Cross EE et al. Identification of a novel Bves function: regulation of vesicular transport. EMBO J 2010-02-03 [PMID: 20057356] (ICC/IF, Canine)	ICC/IF	Canine
Williams D, Pessin JE. Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes. J Cell Biol, 2008;180(2):375-87. 2008-01-28 [PMID: 18227281]
Han J, Yoon S, Park H Vamp3-dependent secretion of endocytic BDNF from astrocytes Research Square 2021-08-04 (ICC/IF, WB, Mouse)	ICC/IF, WB	Mouse
Han J, Yoon S, Park H. Endocytic BDNF secretion regulated by Vamp3 in astrocytes Scientific reports 2021-10-27 [PMID: 34707216] (ICC/IF, Human)	ICC/IF	Human
Tiwari N, Wang C-C, Brochetta C et al. VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways. Blood111(7):3665-74. 2008-04-01 [PMID: 18203950]
Show All 11 Publications. Collapse Publications.

Array NB300-510

• VAMP3/Cellubrevin Antibodies
• VAMP3/Cellubrevin Lysate
• VAMP3/Cellubrevin Protein