Olig2 Antibody [Biotin] Summary
Immunogen
E. coli -derived recombinant human Olig2 Met1-Lys323 Accession # Q13516
Specificity
Detects Olig2 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) Olig1 and rhOlig3 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
OLIG2
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Applications/Dilutions
Dilutions
Immunohistochemistry 5-15 ug/mL Western Blot 0.1 ug/mL
Readout System
Publications
Read Publications using BAF2418 in the following applications:
Packaging, Storage & Formulations
Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Olig2 Antibody [Biotin]
Background
Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors
expressed in the motor neuron progenitor (pMN) domain of the spinal
cord that generates motor neurons and oligodendrocytes. Olig1 is
involved in the development and maturation of oligodendrocytes. Olig2
is required for oligodendrocyte and motor neuron specification in the
spinal cord.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Olig2 Antibody (BAF2418)(4)
We have publications tested in 2 confirmed species: Human, Mouse.
We have publications tested in 2 applications: ICC, IHC.
Submit a Publication
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Showing Publications 1 -
4 of 4.
Publications using BAF2418
Applications
Species
A Xu, M Liu, MF Huang, Y Zhang, R Hu, JA Gingold, Y Liu, D Zhu, CS Chien, WC Wang, Z Liao, F Yuan, CW Hsu, J Tu, Y Yu, T Rosen, F Xiong, P Jia, YP Yang, DA Bazer, YW Chen, W Li, CD Huff, JJ Zhu, F Aguilo, SH Chiou, NC Boles, CC Lai, MC Hung, Z Zhao, EL Van Nostra, R Zhao, DF Lee Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation Nature Communications, 2023-03-27;14(1):1694. 2023-03-27 [PMID: 36973285] (ICC, Human)
ICC
Human
M Komabayash, E Yamanishi, C Watanabe, M Okamura, H Tabata, R Iwai, I Ajioka, J Matsushita, H Kidoya, N Takakura, T Okamoto, K Kinoshita, M Ichihashi, KI Nagata, M Ema, KI Mizutani Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development Cell Rep, 2019-10-29;29(5):1113-1129.e5. 2019-10-29 [PMID: 31665628] (IHC, Mouse)
IHC
Mouse
Emma V. Bird, Tommaso Iannitti, Claire R. Christmas, Ilona Obara, Veselin I. Andreev, Anne E. King et al. A Novel Role for Lymphotactin (XCL1) Signaling in the Nervous System: XCL1 Acts via its Receptor XCR1 to Increase Trigeminal Neuronal Excitability Neuroscience 5/21/2018 [PMID: 29588250]
Mio Oshikawa, Kei Okada, Kazunori Nakajima, Itsuki Ajioka Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner Development 6/1/2013 [PMID: 23615279]
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