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Nse2 Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-76263AF350
Alexa Fluor 405
NBP1-76263AF405
Alexa Fluor 488
NBP1-76263AF488
Alexa Fluor 532
NBP1-76263AF532
Alexa Fluor 594
NBP1-76263AF594
Alexa Fluor 647
NBP1-76263AF647
Alexa Fluor 700
NBP1-76263AF700
Alexa Fluor 750
NBP1-76263AF750
Biotin
NBP1-76263B
CoraFluor 1
NBP1-76263CL1
DyLight 350
NBP1-76263UV
DyLight 405
NBP1-76263V
DyLight 488
NBP1-76263G
DyLight 550
NBP1-76263R
DyLight 594
NBP1-76263DL594
DyLight 650
NBP1-76263C
DyLight 680
NBP1-76263FR
DyLight 755
NBP1-76263IR
FITC
NBP1-76263F
HRP
NBP1-76263H
Janelia Fluor 525
NBP1-76263JF525
Janelia Fluor 549
NBP1-76263JF549
Janelia Fluor 585
NBP1-76263JF585
Janelia Fluor 635
NBP1-76263JF635
Janelia Fluor 646
NBP1-76263JF646
PerCP
NBP1-76263PCP
Unconjugated
NBP1-76263
mFluor Violet 450 SE
NBP1-76263MFV450
mFluor Violet 500 SE
NBP1-76263MFV500
mFluor Violet 610 SE
NBP1-76263MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-76263
BSA Free
NBP1-76263
BSA Free
NBP1-76263-0.025mg
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Nse2 Antibody [Janelia Fluor® 669] Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21. The immunogen is located within amino acids 170 - 220 of MMS21. Amino Acid Squence: CIVRMIESRQKRKKKA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NSMCE2
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine (80%).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Nse2 Antibody [Janelia Fluor® 669]

  • C8orf36
  • E3 SUMO-protein ligase NSE2
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ32440
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • MMS21 homolog
  • MMS21chromosome 8 open reading frame 36
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-SMC element 2 homolog
  • non-SMC element 2, MMS21 homolog (S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2 homolog
  • NSE2

Background

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Nse2 Antibody
[Janelia Fluor®
NBP1-76263JF669
Nse2 Antibody [Janelia Fluor® 669]
Species: Hu, Mu, Rt
Applications: WB, ELISA

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NSMCE2