Species: Hu
Applications: WB, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
286053 |
| Alternate Names |
- C8orf36
- E3 SUMO-protein ligase NSE2
- EC 6.3.2
- EC 6.3.2.-
- FLJ32440
- hMMS21
- methyl methanesulfonate sensitivity gene 21
- MMS21 homolog
- MMS21chromosome 8 open reading frame 36
- non-SMC element 2 homolog (MMS21, S. cerevisiae)
- Non-SMC element 2 homolog
- non-SMC element 2, MMS21 homolog (S. cerevisiae)
- Non-structural maintenance of chromosomes element 2 homolog
- NSE2
|
