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Nse2 Antibody (OTI6A6) [mFluor Violet 610 SE]

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Nse2 Antibody (OTI6A6) [mFluor Violet 610 SE] [NBP2-73070MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF
Clone
OTI6A6
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

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Nse2 Antibody (OTI6A6) [mFluor Violet 610 SE] Summary

Immunogen
Full length human recombinant protein of human NSMCE2 (NP_775956) produced in E.coli.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NSMCE2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Nse2 Antibody (OTI6A6) [mFluor Violet 610 SE]

  • C8orf36
  • E3 SUMO-protein ligase NSE2
  • EC 6.3.2
  • EC 6.3.2.-
  • FLJ32440
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • MMS21 homolog
  • MMS21chromosome 8 open reading frame 36
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-SMC element 2 homolog
  • non-SMC element 2, MMS21 homolog (S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2 homolog
  • NSE2

Background

E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombination by recruiting theSMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteinssuch as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is requiredfor the prevention of DNA damage-induced apoptosis by facilitating DNA repair

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NSMCE2