mTOR antibody

The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein complexes (mTORC1 and mTORC2) capable of regulating cell metabolism, growth, and proliferation.

Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase and has been known to play its role in cell growth and proliferation. mTOR is activated by phosphorylationin response to growth factors, mitogens and hormones. Rapamycin is a macrolide antibiotic from Streptomyces hygroscopicus that specifically inhibit the activity of mTOR.

The protein encoded by mTOR (mammalian target of rapamycin), also known as dTOR in Drosophila, belongs to a family of phosphatidylinositol kinase-related kinases. These kinases regulate fundamental processes of cell growth, proliferation, metabolism

The mammalian target of rapamycin (mTOR) is a downstream effector of the phosphatidylinositol 3-kinase (PI3K)/Akt (protein kinase B) signaling pathway that mediates cell survival and proliferation. It is increasingly apparent that mTOR signaling impacts most major cellular functions.