Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Description
SERCA1 ATPase encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different isoforms.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
487 |
| Alternate Names |
- ATP2A
- ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
- Calcium pump 1
- Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletalmuscle isoform
- EC 3.6.3
- Endoplasmic reticulum class 1/2 Ca(2+) ATPase
- sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- SERCA1EC 3.6.3.8
- SR Ca(2+)-ATPase 1
|
