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Stargazin Antibody (S245-36) [DyLight 350]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clone
S245-36
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Stargazin Antibody (S245-36) [DyLight 350] Summary

Immunogen
Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
Localization
Membrane
Specificity
Detects approx 35-55kDa. Does not cross-react with TARPGamma3.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CACNG2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Stargazin Antibody (S245-36) [DyLight 350]

  • calcium channel, voltage-dependent, gamma subunit 2
  • FLJ41437
  • MGC138502
  • MGC138504
  • Neuronal voltage-gated calcium channel gamma-2 subunit
  • stargazin
  • voltage-dependent calcium channel gamma-2 subunit

Background

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002). Stargazin mutant mice are utilized as a model for absence epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CACNG2