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Human Skin Tissue MicroArray (Cancer)

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Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 01. Skin, Leg Invasive Squamous Cell, Well Differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 01. Skin, Leg Invasive Squamous Cell, Well Differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 02. Skin, Lower leg Squamous Cell Carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 03. Skin, neck squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 04. Skin, foot squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 05. Skin, neck squamous cell carcinoma, moderately diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 06. Skin, face squamous cell carcinoma, moderately diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 07. Skin, shin squamous cell carcinoma, well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 08. Skin, Lower leg squamous cell carcinoma, well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 04. Skin, foot squamous cell carcinoma, well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 10. Skin, neck squamous cell carcinoma, well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 11. Skin, ear, basal cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 12. Skin, inguinal area, squamous cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 13. Skin, buttock squamous cell carcinoma, moderately differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 14. Skin, forearm squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 15. Skin, cheek squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 16. Skin, Perianal squamous cell carcinoma, Well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 17. Skin, lower leg invasive squamous cell carcinoma well diffrentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 18. Skin, thumb squamous cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 19. Skin, lip squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 20. Skin, lower leg squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 21. Skin, lower leg squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 22. Skin, left malleolus squamous cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 23. Skin, scalp squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 24. Squamous cell carcinoma, well differentiated.
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - - 25. Skin, lower lip squamous cell carcinoma, moderately differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 26. Skin thigh basal cell carcinoma mixed type
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 27. Skin, foot verrucous carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 29.Vulva microinvasive squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 31.Skin, scalp basal cell carcinoma with adnexal differentiation
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 32. Skin, cheek squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 30. Skin, planta squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 34.Skin, thigh squamous cell carcinoma, recurrent
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 36. Skin, ear basal cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 37.Skin, arm squamous cell carcinoma, moderately differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 38.Skin, face basal cell carcinoma
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 39. Tongue squamous cell carcinoma, well differentiated
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 40. Skin, flank Bowen's disease
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 41.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 42.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 43.Skin normal of No. 37
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 44.Skin normal of No. 23
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 45.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 46.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 47.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 49.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 48.Skin normal
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 09. Skin, sacral area squamous cell carcinoma, well differentiated T1N0M0
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - 28. Skin, neck squamous cell carcinoma, well differentiated T2N0M0
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - Skin, neck squamous cell carcinoma, well differentiated T1N1M0
Hematoxylin & Eosin Stain: Human Skin Tissue MicroArray (Cancer) [NBP2-30229] - Skin, chest wall squamous cell carcinoma, moderately differentiated T2N1M1

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC

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Human Skin Tissue MicroArray (Cancer) Summary

Description
Microarray Panel:
Skin cancer-normal
No. of samples: 49
No. of patients: 47
Core diameter: 2.0 mm
Format: Formalin Fixed
Section thickness: 4 micrometer
Please see manual for tissue information and location.

All tissues are fixed in 10% neutral buffered formalin for 12 to 24 hours, dehydrated with gradient ethanol, cleared with xylene, and embedded in paraffin. Then each slide is tested for immunohistochemistry on multiple antibodies including the p53 protein. Quality control is ensured as every tissue block is collected and arranged by certified pathologists, who used an identical process for their own research.

About 100,000 cells are included in each sample with 2 mm core diameter. Some slides may have less than 60 cores due to sample loss when obtaining multiple sections. Maximum number of missing cores in a slide is less than 10%.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID 27859308)
Publications
Read Publications using
NBP2-30229 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.

Details for Array

Type
Tissue
Tissue Condition
Cancer

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Tissue Micro Arrays are guaranteed for 1 year from date of receipt.

Publications for Skin Tissue Micro Array (NBP2-30229)(6)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, IHC-P.


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IF/IHC
(1)
IHC-P
(5)
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Human
(4)
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Showing Publications 1 - 6 of 6.
Publications using NBP2-30229 Applications Species
Janda J, Burkett NB, Blohm-Mangone K et al. Resatorvid-based Pharmacological Antagonism of Cutaneous TLR4 Blocks UV-induced NF-kB and AP-1 Signaling in Keratinocytes and Mouse Skin. Photochem. Photobiol. 2016-11-10 [PMID: 27859308] (IF/IHC, Human) IF/IHC Human
Liu L, Rezvani HR, Back JH et al. Inhibition of p38 MAPk Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation. PLoS ONE. 2014-05-14 [PMID: 24824222] (IHC-P, Human)

Details:
Fig 1C,D. The TMA was stained with a p38 alpha antibody. The signal intensity and the extent of staining were quantified using the pixel analysis function of Adobe Photoshop. 		IHC-P Human
Williams JD, Bermudez Y, Park SL et al. Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue. J. Photochem. Photobiol. B, Biol. 2014-02-12 [PMID: 24584085] (IHC-P, Human)

Details:
IHC (P), IMH-323, Lot CX2 was used, Fig 4. 		IHC-P Human
Brennan D, Mahoney MG. Increased expression of Dsg2 in malignant skin carcinomas: A tissue-microarray based study. Cell Adh Migr. 2009-04-01 [PMID: 19458482] (IHC-P, Human)

Details:
Human skin cancer histo-array (IMH-323). IHC (paraffin): Labeled with Dsg2 antibody, Fig 4. 		IHC-P Human
Schacht V, Dadras SS, Johnson LA et al. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005-03-01 [PMID: 15743802] (IHC-P)

Details:
IHC (paraffin), Figs. 3A-H, 4A-L, 5A-J. 		IHC-P
Bonuccelli G, Sotgia F, Frank PG et al. ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection. Am J Physiol Cell Physiol. 2005-06-01 [PMID: 15689409] (IHC-P)

Details:
IHC (paraffin): 1. IMH-323 (Human Skin Cancer Histo-Array), Fig. 7A, B. 2. IMH-340 (Lung, matching normal adjacent tissues of IMH-305), Fig. 6A, B. 		IHC-P

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Skin Tissue Micro Array (NBP2-30229). (Showing 1 - 2 of 2 FAQs).

  1. For adult normal frozen skin tissue slides can I choose the donor age/sex? 
    • Unfortunately, that is not an option for our commercially available tissue slides.
  2. On the web page of NBP2-30229, I can find the patients' information including age, gender, tumor location, diagnosis, pTNM and tissue type. Would you please indicate the meaning of code of tissue type? Also, do you have more detail information about the patients on the tissue microarry?
    • The tissue codes on our information for tissue microarray NBP2-30229 are translated as follows: 1. Normal tissue from a non-cancer patient  2. Normal tissue form a cancer patient, but the cancer involves unrelated organs  3. Normal tissue adjacent to the cancer  4. Benign tumor  5. Tumor of borderline malignancy or uncertain malignant potential  6. Cancer                                   When purchased, the datasheet for the microarray will contain a password and website where you can obtain supplementary data for the donors of the tissues.

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Product PDFs

  Manual - Human Skin Tissue MicroArray (Cancer)
  TMA IHC Protocol
  PDF Datasheet
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