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Serpin D1/Heparin Cofactor II Antibody (008) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
008
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 488

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Serpin D1/Heparin Cofactor II Antibody (008) [Alexa Fluor® 488] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Serpin D1/Heparin Cofactor II (Accession#: NP_000176.2; Met1-Ser499).
Specificity
Has cross-reactivity in ELISA with:

Mouse SerpinD1
No cross-reactivity in ELISA with:

Human SerpinA3
Human SerpinC1
Human SerpinI1
Mouse SerpinF1
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
SERPIND1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Serpin D1/Heparin Cofactor II Antibody (008) [Alexa Fluor® 488]

  • HC2
  • HC2LS2
  • HCF2
  • HCF2clade D (heparin cofactor), member 1
  • HC-II
  • Heparin Cofactor II
  • HLS2HCII
  • leuserpin 2
  • LS2
  • Protease inhibitor leuserpin-2
  • Serpin D1
  • serpin peptidase inhibitor, clade D (heparin cofactor), member 1

Background

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SERPIND1