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MSH6 Antibody [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP (-)
Clonality
Polyclonal
Host
Goat
Conjugate
DyLight 350

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MSH6 Antibody [DyLight 350] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 350 and 400 of human MutS homolog 6 using the numbering given in entry NP_000170.1 (GeneID 2956).
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MSH6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MSH6 Antibody [DyLight 350]

  • DNA mismatch repair protein Msh6
  • G/T mismatch-binding protein
  • GTBPHNPCC5
  • GTMBP
  • hMSH6
  • HSAP
  • mutS (E. coli) homolog 6
  • mutS homolog 6 (E. coli)
  • MutS-alpha 160 kDa subunit
  • p160
  • sperm-associated protein

Background

MSH6 is a mismatch-repair protein. It plays a role in tumor suppression. Genomic mutations in MSH6 predispose to the hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for MSH6 Antibody (NB100-328UV). (Showing 1 - 1 of 1 FAQ).

  1. I am testing a mouse sample with human xenograft for GBM and I am looking for an MSH6 Antibody that will only detect the human cells.
    • Currently, we have no validation that any of our MSH6 antibodies will not cross react with mouse. All of our MSH6 Antibodies are raised against Human MSH6 so we have checked the % homology with mouse MSH6 which has come to be 85%. As 85% is very high, the chances of the antibody detecting the mouse tissue as well as the human tissue are high.

Secondary Antibodies

 

Isotype Controls

Additional MSH6 Products

Array NB100-328UV

Research Areas for MSH6 Antibody (NB100-328UV)

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Bioinformatics

Gene Symbol MSH6