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MSH6 Antibody (MSH6/3086) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, MA, CyTOF-ready
Clone
MSH6/3086
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-79846AF350
Alexa Fluor 405
NBP2-79846AF405
Alexa Fluor 488
NBP2-79846AF488
Alexa Fluor 532
NBP2-79846AF532
Alexa Fluor 594
NBP2-79846AF594
Alexa Fluor 647
NBP2-79846AF647
Alexa Fluor 700
NBP2-79846AF700
Alexa Fluor 750
NBP2-79846AF750
Allophycocyanin
NBP2-79846APC
Biotin
NBP2-79846B
CoraFluor 1
NBP2-79846CL1
DyLight 350
NBP2-79846UV
DyLight 405
NBP2-79846V
DyLight 488
NBP2-79846G
DyLight 550
NBP2-79846R
DyLight 594
NBP2-79846DL594
DyLight 650
NBP2-79846C
DyLight 680
NBP2-79846FR
DyLight 755
NBP2-79846IR
FITC
NBP2-79846F
HRP
NBP2-79846H
Janelia Fluor 525
NBP2-79846JF525
Janelia Fluor 549
NBP2-79846JF549
Janelia Fluor 646
NBP2-79846JF646
PE
NBP2-79846PE
PerCP
NBP2-79846PCP
Unconjugated
NBP2-79712-100ug
mFluor Violet 450 SE
NBP2-79846MFV450
mFluor Violet 500 SE
NBP2-79846MFV500
mFluor Violet 610 SE
NBP2-79846MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-79712-100ug
Azide and BSA Free
NBP2-79846
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MSH6 Antibody (MSH6/3086) [Janelia Fluor® 669] Summary

Immunogen
Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary) (Uniprot: P52701)
Localization
Nucleus
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MSH6
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Protein Array
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MSH6 Antibody (MSH6/3086) [Janelia Fluor® 669]

  • DNA mismatch repair protein Msh6
  • G/T mismatch-binding protein
  • GTBPHNPCC5
  • GTMBP
  • hMSH6
  • HSAP
  • mutS (E. coli) homolog 6
  • mutS homolog 6 (E. coli)
  • MutS-alpha 160 kDa subunit
  • p160
  • sperm-associated protein

Background

MSH6 is a mismatch-repair protein. It plays a role in tumor suppression. Genomic mutations in MSH6 predispose to the hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for MSH6 Antibody (NBP2-79846JF669). (Showing 1 - 1 of 1 FAQ).

  1. I am testing a mouse sample with human xenograft for GBM and I am looking for an MSH6 Antibody that will only detect the human cells.
    • Currently, we have no validation that any of our MSH6 antibodies will not cross react with mouse. All of our MSH6 Antibodies are raised against Human MSH6 so we have checked the % homology with mouse MSH6 which has come to be 85%. As 85% is very high, the chances of the antibody detecting the mouse tissue as well as the human tissue are high.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol MSH6