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Lymphotoxin beta R/TNFRSF3 Antibody (157108) [DyLight 550]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
157108
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB10081U-100UG
Alexa Fluor 405
FAB10081V-100UG
Alexa Fluor 488
FAB10081G-100UG
Alexa Fluor 532
FAB10081X
Alexa Fluor 594
FAB10081T-100UG
Alexa Fluor 647
FAB10081R-100UG
Alexa Fluor 700
FAB10081N-100UG
Alexa Fluor 750
FAB10081S-100UG
Allophycocyanin
FAB10081A
Allophycocyanin/Cy7
FAB10081APCCY7
Biotin
FAB10081B
DyLight 350
FAB10081D
DyLight 405
FAB10081E
DyLight 488
FAB10081K
DyLight 594
FAB10081M
DyLight 650
FAB10081W
DyLight 680
FAB10081Y
DyLight 755
FAB10081Z
FITC
FAB10081F
HRP
FAB10081H
Janelia Fluor 549
FAB10081I
Janelia Fluor 646
FAB10081J
PE/Atto594
FAB10081PEATT594
PE/Cy5.5
FAB10081PECY55
PE/Cy7
FAB10081PECY7
PerCP
FAB10081C
Unconjugated
MAB10081
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10081
Carrier Free
MAB10081
Carrier Free
MAB10081-SP
Carrier Free
FAB10081V-100UG
Carrier Free
FAB10081U-100UG
Carrier Free
FAB10081T-100UG
Carrier Free
FAB10081S-100UG
Carrier Free
FAB10081R-100UG
Carrier Free
FAB10081N-100UG
Carrier Free
FAB10081G-100UG
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Lymphotoxin beta R/TNFRSF3 Antibody (157108) [DyLight 550] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Lymphotoxin beta R/TNFRSF3
Ser28-Pro218
Accession # P50284
Specificity
Detects mouse Lymphotoxin beta R in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant mouse (rm) 4‑1BB, rmBAFF R, rmCD27, rmCD30, rmCD40, recombinant human (rh) DR3, rhDR6, rmEDAR, rmFas, rmGITR, rmHVEM, rhLymphotoxin  beta R, rmNGF R, rmOPG, rmOX40, rmRANK, rhRELT, rmTAJ, rmTNF RI, rmTNF RII, rhTRADD, rmTRAIL R2, rhTRAIL R3, rhTRAIL R4, or rmTWEAK R.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
LTBR
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Lymphotoxin beta R/TNFRSF3 Antibody (157108) [DyLight 550]

  • CD18
  • D12S370
  • ltbetar
  • LT-BETA-R
  • LTBR
  • lymphotoxin B receptor
  • Lymphotoxin beta R
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
  • Lymphotoxin-beta receptor
  • LymphotoxinbR
  • TNF RIII
  • TNF Rrp
  • TNFCRTNF-RIII
  • TNFR superfamily, member 3
  • TNFR2-RP
  • TNFR3
  • TNF-R-III
  • TNFR-RP
  • TNFRSF3
  • TNFRSF3TNFR-III
  • Tumor necrosis factor C receptor
  • Tumor necrosis factor receptor 2-related protein
  • tumor necrosis factor receptor superfamily member 3
  • tumor necrosis factor receptor superfamily, member 3
  • Tumor necrosis factor receptor type III

Background

LT-beta-R, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member 3 is a 47 kD transmembrane protein containing 3 TNF receptor domains. The LT-beta-R is a receptor for the heterotrimeric lymphotoxin complex (composed of LT alpha and LT beta as well as LIGHT. LT-beta-R is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-beta-R is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-beta-R interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-beta-R has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Lymphotoxin beta R/TNFRSF3 Antibody (FAB10081L) (0)

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Secondary Antibodies

 

Isotype Controls

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Calculators

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Bioinformatics

Gene Symbol LTBR