IL-2 R beta Antibody (130122) [DyLight 350]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
130122
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 350

Order Details

IL-2 R beta Antibody (130122) [DyLight 350] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-2 R beta
Ala27-Glu240
Accession # P16297
Specificity
Detects mouse IL-2 R beta in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL‑2 R alpha , rhIL-2 R beta , recombinant mouse (rm) IL-2 R gamma , rhIL-15 R alpha , or rmIL-21 R is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
IL2RB
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-2 R beta Antibody (130122) [DyLight 350]

  • CD122 antigen
  • CD122
  • high affinity IL-2 receptor beta subunit
  • High affinity IL-2 receptor subunit beta
  • IL-15 R beta
  • IL-2 R beta
  • IL-2 receptor subunit beta
  • IL2R beta
  • IL-2R subunit beta
  • IL2RB
  • IL-2Rb
  • interleukin 15 receptor, beta
  • interleukin 2 receptor, beta
  • interleukin-2 receptor subunit beta
  • P70-75
  • p75

Background

The Interleukin 2 Receptor alpha and beta chains, together with the common gamma chain, constitute the high affinity IL2 receptor present on activated T and B cells, thymocyte subset, pre B cells and T regulatory cells. Homodimeric alpha chains result in low affinity receptor, while homodimeric beta chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2 Receptor alpha has been isolated and determined to result from extracellular proteolysis. Alternately spliced IL2 Receptor alpha mRNAs have been isolated, but the significance of each is presently unknown.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for IL-2 R beta Antibody (FAB5891D) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL2RB