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Rat IgG1 Isotype Control (HPN33)

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Product Details

Summary
Reactivity RtSpecies Glossary
Clone
HPN33
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Rat IgG1 Isotype Control (HPN33) Summary

Description
This Rat IgG1 (HPN33) immunoglobulin is useful as an isotype control for Rat IgG1 (HPN33) antibody. This antibody is purified from culture supernatant of a hybridoma (Mouse myeloma fused with spleen cells from a Rat, clone HPN33) with protein A/G beads.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Purity
Protein A or G purified

Applications/Dilutions

Application Notes
Use the isotype control at the same concentration as the experimental antibody. Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered solution in PBS. 0.5 mg and 250 ug sizes are provided in liquid form, PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified
Reconstitution Instructions
Reconstitute with PBS.

Alternate Names for Rat IgG1 Isotype Control (HPN33)

  • IgG1
  • Igh-4
  • RGD1359539
  • VH7183

Background

IgG is a monomeric immunoglobulin composed of two heavy chains and two light chains. There are four subclasses of the IgG: IgG1, IgG2, IgG3 and IgG4. Each molecule has two antigen binding sites. IgG is the most abundant immunoglobulin as well as the only isotype that can pass through the placent,a thereby providing protection to the fetus in its first weeks of life before, its own immune system has developed. IgG can bind to several different kinds of pathogens, for example viruses, bacteria and fungi, and it protects the body against them by complement activation (the classic pathway), opsonization for phagocytosis and neutralization of their toxins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

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