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Fibroblast Antibody (ER-TR7) [DyLight 594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC
Clone
ER-TR7
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 594

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Support & Research

Fibroblast Antibody (ER-TR7) [DyLight 594] Summary

Immunogen
Isolated C3H thymic stromal cells
Marker
Fibroblast Marker
Specificity
NB100-64932 recognizes ER-TR7, an antigen that is located in the cytoplasm of reticular fibroblasts and is a component of the extracellular matrix of lymphoid and non-lymphoid organs. The antigen recognized by clone ER-TR7 has not been identified but studies suggest that it is likely to be distinct from laminin, fibronectin, collagen types I-IV, heparin sulphate proteoglycan, entactin and nidogen. Clone ER-TR7 has been used to stain the microanatomy of various organs and also stains subendothelial deposits in atherosclerotic plaques.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Fibroblast Antibody (ER-TR7) [DyLight 594]

  • reticular fibroblast

Background

A fibroblast is a cell that synthesizes collagen and the extracellular matrix. Inactive fibroblasts are known as fibrocytes. Fibroblasts are important in healing wounds, and their mitosis is induced by tissue damage. Fibroblasts can be identified by their high levels of rough endoplasmic reticulum. They are also the most common connective tissue cells in animals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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