Reactivity | HuSpecies Glossary |
Applications | WB, ELISA, Flow, ICC/IF, B/N |
Clone | 1C1 |
Clonality | Monoclonal |
Host | Human |
Conjugate | Janelia Fluor 635 |
Additional Information | Recombinant Monoclonal Antibody |
Immunogen | 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1. |
Specificity | 1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Human |
Gene | EPHA2 |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for EphA2 Antibody (NBP2-81069JF635)Find related products by research area.
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Repurposing FDA-approved drugs to combat the rise of antibiotic resistance By Beth Melson, MSAntibiotic resistance is a global threat to public health. Widespread, inappropriate use of antibiotics, such as to treat viral infections or promote growth in livestock, has led to increased incid... Read full blog post. |
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Gene Symbol | EPHA2 |