![Cytokeratin 8/18 Antibody (SPM141) [mFluor Violet 610 SE] [NBP3-11564MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.](http://images.novusbio.com/fullsize/nbp3-11564mfv610_mouse-cytokeratin-8-18-mab-spm141-mfluor-violet-610-se-672023859838.png "Cytokeratin 8/18 Antibody (SPM141) [mFluor Violet 610 SE] [NBP3-11564MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.")
| Reactivity | HuSpecies Glossary |
| Applications | WB, Flow, ICC/IF, IHC, ICC/IF |
| Clone | SPM141 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | mFluor Violet 610 SE |
| Immunogen | Keratin preparation from human breast carcinoma MCF-7 cells |
| Localization | Cytoplasmic |
| Specificity | Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. |
| Isotype | IgG1 Kappa |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | KRT8 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Cytokeratin 8/18 Antibody (NBP3-11564MFV610)Find related products by research area.
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| Gene Symbol | KRT8 |
