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CA125/MUC16 Antibody (986811) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
986811
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

CA125/MUC16 Antibody (986811) [Janelia Fluor® 646] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16
Met13360-Gln14347 (Met13472Thr & Gln13957Lys)
Accession # NP_078966.2
Specificity
Detects human CA125/MUC-16 in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for CA125/MUC16 Antibody (986811) [Janelia Fluor® 646]

  • CA125 ovarian cancer antigen
  • CA125
  • CA-125
  • CA125MUC-16
  • FLJ14303
  • MUC16
  • mucin 16, cell surface associated
  • mucin-16
  • Ovarian cancer-related tumor marker CA125
  • Ovarian carcinoma antigen CA125

Background

MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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