AICDA Antibody

Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NB100-93454	Applications	Species
Nair L, Zhang W, Laffleur B Et al. Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination Molecular cell 2021-08-20 [PMID: 34450044] (ICC/IF, Mouse)	ICC/IF	Mouse
Crouch EE, Li Z, Takizawa M et al. Regulation of AID expression in the immune response. J Exp Med 2007-05-14 [PMID: 17452520]

Array NB100-93454

• AICDA Antibodies
• AICDA Lysate
• AICDA Proteins