Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Chicken Polyclonal
Species: Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex. which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5. instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues. which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC. the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Bioinformatics
Uniprot |
Human Human Human |
Product By Gene ID |
54433 |
Alternate Names |
- GAR1 ribonucleoprotein homolog (yeast)
- H/ACA ribonucleoprotein complex subunit 1
- NOLA1member 1 (H/ACA small nucleolar RNPs)
- Nucleolar protein family A member 1
- snoRNP protein GAR1
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