Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
NCOR encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
9611 |
| Alternate Names |
- hN-CoR
- KIAA1047N-CoR1
- MGC104216
- N-CoRhCIT529I10
- nuclear receptor corepressor 1
- nuclear receptor co-repressor 1
- thyroid hormone- and retinoic acid receptor-associated corepressor 1
- TRAC1
|
Related NCOR1 Blog Posts
Check out the latest blog posts on NCOR1.
NCOR & EZH2 in Muscular Dystrophy
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur... Read more.
|
Muscular Dystrophy Regulation: Ezh2, NCoR-1
Over the years muscular dystrophies have become a popular area of research. These are a group of inherited disorders that involve an increase in muscle weakness over time. These disorders greatly decrease the quality of life and there are no known cur... Read more.
|
Read more NCOR1 related blogs.
![Western Blot NCOR1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/NCOR1_AF6167_Western_Blot_9559.jpg)
