IRE1 Products

Description

IRE1 is encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. IRE1 possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Bioinformatics

Entrez	2081 Human
Uniprot	AAC25991 Human NP_001424.3 Human O75460 Human
Product By Gene ID	2081
Alternate Names	EC 2.7.11 endoplasmic reticulum to nucleus signaling 1 Endoplasmic reticulum-to-nucleus signaling 1 ER to nucleus signalling 1 FLJ30999 hIRE1p inositol-requiring 1 Inositol-requiring protein 1 IRE1a Ire1-alpha ire1-alpha IRE1MGC163279 IRE1P MGC163277 protein kinase/endoribonuclease serine/threonine-protein kinase/endoribonuclease IRE1

Research Areas for IRE1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Biology
Diabetes Research
Hypoxia
Lipid and Metabolism
Neuroscience
Phospho-Specific
Unfolded Protein Response

Related IRE1 Blog Posts

Check out the latest blog posts on IRE1.

IRE1: Apoptosis, Autophagy and ER Stress Response IRE1 resides in the endoplasmic reticulum (ER) as a transmembrane protein with both serine-threonine kinase and endoribonuclease activities. It acts as an unfolded protein response (UPR) sensor through XBP1 transcriptional activation and has been foun...    Read more.

Read more IRE1 related blogs.