ERK1 Products

Description

p44 MAP Kinase (Erk1) is a member of a family of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth and differentiation (1,2). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) (3). Erk1 is also known to autophosphorylate on tyrosine (3).

Bioinformatics

Entrez	26417 Mouse 50689 Rat 5595 Human
Uniprot	AAH13992 Human AAH13992.1 Human NM_002746 Human NP_002737 Human NP_002737 Human NP_002737.2 Human P27361 Human P27361 Human
Product By Gene ID	5595
Alternate Names	EC 2.7.11 ERK-1 ERK1p44-MAPK ERT2 Extracellular signal-regulated kinase 1 extracellular signal-related kinase 1 HS44KDAP HUMKER1A Insulin-stimulated MAP2 kinase MAP kinase 1 MAP kinase 3 MAP kinase isoform p44 MAPK 1 MAPK 3 MGC20180 Microtubule-associated protein 2 kinase Mitogen-activated protein kinase 1 mitogen-activated protein kinase 3 p44erk1 P44ERK1 p44-ERK1 P44MAPK p44mapk PRKM3EC 2.7.11.24

Research Areas for ERK1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Cell Cycle and Replication
Diabetes Research
Hypoxia
MAP Kinase Signaling
mTOR Pathway
Phospho-Specific
Signal Transduction

Related ERK1 Blog Posts

Check out the latest blog posts on ERK1.

The effects of curcumin on IKB Alpha and the NFkB signaling pathway The IKK complex, or inhibitor of NFkB kinase, is composed of IKK alpha and IKK beta.  These kinases are at the core of the NFkB signaling cascade.  The NFkB family is made up of transcription factors that are kept inactive in the cytoplasm through...    Read more.

The role of c-Fos in the regulation of the JC virus gene transcription c-Fos is a member of the AP-1 transcription factor family under the Fos protein family umbrella, alongside Fra-1, Fra-2 and Fos-B.  Also in the AP-1 transcription family are the Jun proteins, c-Jun, Jun-B and Jun-D.  Each member of the AP-1 transcri...    Read more.

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MAPK3/ERK1 - A signal transduction pathway with roles in development and disease Mitogen-activated protein kinases (MAPKs) are important signaling proteins needed to transmit and relay extracellular stimuli and to illicit intracellular responses (1). The MAPK family of proteins are serine/threonine kinases that are able to phos...    Read more.

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