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Crigler-najjar Syndrome: Disease Bioinformatics

Research of Crigler-najjar Syndrome has been linked to Hyperbilirubinemia, Gilbert Disease (disorder), Hyperbilirubinemia, Hereditary, Icterus, Unconjugated Hyperbilirubinemia. The study of Crigler-najjar Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Crigler-najjar Syndrome include Excretion, Conjugation, Bilirubin Conjugation, Transport, Immune Response. These pathways complement our catalog of research reagents for the study of Crigler-najjar Syndrome including antibodies and ELISA kits against UDP GLUCURONOSYLTRANSFERASE, SPHEROCYTOSIS, ALB, FECH, G6PD.

Top Research Reagents

We have 936 products for the study of Crigler-najjar Syndrome that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

UGT1A9 Antibody
H00054600-B01P
Western Blot: UGT1A9 Antibody [H00054600-B01P] - Analysis of UGT1A9 expression in human liver.Immunohistochemistry-Paraffin: UGT1A9 Antibody [H00054600-B01P] - Analysis of purified antibody to UGT1A9 on formalin-fixed paraffin-embedded human small Intestine. (antibody concentration 3 ug/ml)

Mouse Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

     1 Review

3 Publications
Glucose 6 Phosphate Dehydrogenase Antibody
NB100-236
Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Immunoblot analyses of protein expression for Nrf2 and antioxidant enzymes. Representative immunoblots of cytosolic extracts from the hearts of young and old mice under basal conditions and following EES. Protein blots were probed with anti-HO1, NQO1, GCLM, GCLC, Catalase, SOD1, SOD2, GSR, G6PD, GPX1 and GAPDH. Individual lanes indicate a single animal. Densitometry analysis of respective protein signals was performed using Image-J and expressed as relative intensity units calculated as mean values of young and old, *p<0.05. Individual lanes indicate each animal (n?=?6). #p<0.05-between basal and EES. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0045697), licensed under a CC-BY license.Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Detection of Human and Mouse G6PD by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-G6PD antibody NB100-236 used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IB, IHC

19 Publications
UGT1A6 Antibody
NBP1-33743
Western Blot: UGT1A6 Antibody [NBP1-33743] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with UGT1A6 antibody diluted by 1:1000.Immunohistochemistry-Paraffin: UGT1A6 Antibody [NBP1-33743] - Paraffin-embedded OV90 xenograft, using antibody at 1:100 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

SLC45A2 Antibody
NBP1-59786
Western Blot: SLC45A2 Antibody [NBP1-59786] - Human Fetal Liver, Antibody Dilution: 1.0 ug/ml.Western Blot: SLC45A2 Antibody [NBP1-59786] - Titration: 0.2-1 ug/ml Positive Control: Jurkat cell lysate.

Rabbit Polyclonal
Species Human
Applications WB

UGT Antibody
NBP1-80642
Immunocytochemistry/Immunofluorescence: UGT Antibody [NBP1-80642] - Staining of human cell line A-431 shows localization to the Golgi apparatus. Antibody staining is shown in green.Immunohistochemistry-Paraffin: UGT Antibody [NBP1-80642] - Staining of human Cerebral cortex shows moderate granular cytoplasmic positivity in neuronal and glial cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

1 Publication
Glutaminyl-peptide Cyclotransferase/QPCT Antibody
NBP1-81838
Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Staining in human adrenal gland and liver tissues using anti-QPCT antibody. Corresponding QPCT RNA-seq data are presented for the same tissues.Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Analysis in human cell line SK-MEL-30.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IHC, IHC-P

1 Publication
Ornithine Carbamoyltransferase Antibody
NBP1-87408
Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining in human liver and kidney tissues . Corresponding OTC RNA-seq data are presented for the same tissues.Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-87408] - Staining of human cerebral cortex, kidney, liver and small intestine using Anti-OTC antibody NBP1-87408 (A) shows similar protein distribution across tissues to independent antibody NBP1-88121 (B).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

5 Publications
UGT1A10 Overexpression Lysate
NBP2-06724
Western Blot: UGT1A10 Overexpression Lysate (Adult Normal) [NBP2-06724] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UGT1A10.


Species Human
Applications WB

FECH Antibody
NBP2-33413
Western Blot: FECH Antibody [NBP2-33413] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MGImmunohistochemistry-Paraffin: FECH Antibody [NBP2-33413] - Staining of human lymph node shows no positivity in germinal center cells as expected.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
Serpin A3N Antibody [Unconjugated]
AF4709

Goat Polyclonal
Species Mouse
Applications WB, IP

32 Publications
Albumin Antibody (188835) [Unconjugated] - Serum
MAB1455
Western blot shows lysate of human liver tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Albumin was detected in immersion fixed BG01V human embryonic stem cells differentiated to hepatocytes using Mouse Anti-Human Serum Albumin Monoclonal Antibody (Catalog # MAB1455) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, Simple Western, IHC

     3 Reviews

54 Publications
IBSP/Sialoprotein II [Unconjugated]
4014-SP
Recombinant Human IBSP/Sialoprotein II Protein (Catalog # 4014-SP) supports the adhesion of MCF‑7 human breast cancer cells. The ED<sub>50</sub> for this effect is 0.0600-0.600 µg/mL.


Species Human
Applications BA

5 Publications
beta-Galactosidase-1/GLB1 Antibody (OTI1C9)
NBP2-45731
Western Blot: beta-Galactosidase-1/GLB1 Antibody (OTI1C9) [NBP2-45731] - Analysis of extracts (35ug) from 9 different cell lines by using anti-GLB1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).Immunohistochemistry: beta-Galactosidase-1/GLB1 Antibody (1C9) [NBP2-45731] - Analysis of Adenocarcinoma of Human ovary tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Mouse Monoclonal
Species Human, Canine, Monkey
Applications WB, IHC, IHC-P

6 Publications
UGT1A3 Antibody (1C10)
H00054659-M02
ELISA: UGT1A3 Antibody (1C10) [H00054659-M02] - Detection limit for recombinant GST tagged UGT1A3 is 1 ng/ml as a capture antibody.

Mouse Monoclonal
Species Human
Applications WB, ELISA

4 Publications
NT5C2 Antibody (3C1)
H00022978-M02
Western Blot: NT5C2 Antibody (3C1) [H00022978-M02] - Analysis of NT5C2 expression in transfected 293T cell line by NT5C2 monoclonal antibody (M02), clone 3C1.Lane 1: NT5C2 transfected lysate(64.97 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: NT5C2 Antibody (3C1) [H00022978-M02] - Analysis of monoclonal antibody to NT5C2 on HeLa cell . Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

8 Publications
Glucuronosyltransferase 1A1/UGT1A1 Antibody - Azide and BSA Free
NBP3-03338
Western Blot: Glucuronosyltransferase 1A1/UGT1A1 Antibody [NBP3-03338] - Analysis of extracts of Rat liver, using UGT1A1 antibody at 1:2130 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit. Exposure time: 20s.Immunocytochemistry/Immunofluorescence: Glucuronosyltransferase 1A1/UGT1A1 Antibody [NBP3-03338] - Analysis of human liver cells using UGT1A1 Rabbit pAb at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

UGT1A4 Antibody - Azide and BSA Free
NBP2-94266
Western Blot: UGT1A4 Antibody [NBP2-94266] - Analysis of extracts of various cell lines, using UGT1A4 at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 1s.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB

NT5C1A Antibody
NBP3-06431
Western Blot: NT5C1A Antibody [NBP3-06431] - Anti-NT5C1A rabbit polyclonal antibody at 1:500 dilution. Lane A: MCF7 Whole Cell Lysate Lane B: A549 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Observed band size:44 kDa.Immunohistochemistry-Paraffin: NT5C1A Antibody [NBP3-06431] - Immunochemical staining of human NT5C1A in cynomolgus heart with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

Rabbit Polyclonal
Species Human, Cynomolgus Monkey
Applications WB, IHC, IHC-P


Related Genes

Crigler-najjar Syndrome has been researched against:

Related Pathways

Crigler-najjar Syndrome has been linked to:

Related Diseases

Crigler-najjar Syndrome has been studied in relation to diseases such as:

Related PTMs

Crigler-najjar Syndrome has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Crigler-najjar Syndrome is also known as crigler-najjar syndrome, crigler-najjar syndrome, type i, crigler-najjar syndrome (disorder), familial nonhemolytic unconjugated hyperbilirubinemia, bilirubin udp glucuronyl transferase deficiency, crigler-najjar syndrome, type i (disorder), hereditary unconjugated hyperbilirubinemia, crigler najjar syndrome, type 1, hyperbilirubinemia, hereditary, gilbert disease (disorder), crigler najjar syndrome.