XRCC2 Products

Description

RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. There are five human homologues of RAD51; XRCC2, XRCC3, RAD51B, RAD51C, RAD51D, and they interact among themselves to form one big complex or several smaller complexes. XRCC2 (X Ray Repair Cross Complementing 2), a component of the homologous recombination pathway, is essential for repairing the double strand DNA breaks by homologous recombination between sister chromatids.

Bioinformatics

Entrez	7516 Human
Uniprot	AAH42137 Human NM_005431 Human NP_005422 Human NP_005422.1 Human O43543 Human
Product By Gene ID	7516
Alternate Names	DKFZp781P0919 DNA repair protein XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 X-ray repair cross-complementing protein 2 X-ray repair, complementing defective, repair in Chinese hamster

Research Areas for XRCC2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
DNA Repair
Homologous Recombination
Tumor Suppressors