UCP4 Products

Description

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions.

Bioinformatics

Entrez	74011 Mouse 9481 Human
Uniprot	AAH33091 Human NP_004268 Human O95847 Human Q9D6D0 Mouse
Product By Gene ID	9481
Alternate Names	FLJ33552 mitochondrial uncoupling protein 4 Solute carrier family 25 member 27 solute carrier family 25, member 27 UCP 4 UCP4uncoupling protein 4