Species: Hu
Applications: WB, B/N, ELISA(Cap)
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, B/N, ICC/IF
Host: Mouse Monoclonal
Species: Mu
Applications: WB, ELISA, Flow, CyTOF-ready, ICC/IF
Host: Goat Polyclonal
Species: Mu
Applications: ELISA
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Mu, Rt
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
Tumor Necrosis Factor (TNF) is a cytokine whose function is mediated through two distinct cell surface receptors (TNF Receptor I and TNF Receptor II) that are included in the TNF receptor superfamily along with FAS antigen and CD40. TNF receptors I and II are 55 and 75 kDa members, respectively, of a family of cell surface molecules including nerve growth factor receptor, Fas/Apo1, CD30, OX40, and 4-1BB, which are characterized by cysteine rich motifs in the extracellular domain. TNF Receptor II (p75, CD120b) is present on most cell types (including monocytes, endothelial cells, Langerhans cells, and macrophages) and is considered to play a role in cell stimulation by TNF alpha. TNF Receptor II molecule is shown to be responsible for stimulation of activated T lymphocytes by TNF alpha.
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
7133 |
Alternate Names |
- CD120b antigen
- CD120b
- Etanercept
- p75 TNF receptor
- p75TBPII
- p75TNFR
- soluble TNFR1B variant 1
- TNFBRp80 TNF-alpha receptor
- TNF-R2
- TNFR2TNFR1B
- TNF-R75
- TNFR80
- TNF-RII
- TNF-R-II
- TNFR-II
- tumor necrosis factor beta receptor
- tumor necrosis factor binding protein 2
- Tumor necrosis factor receptor 2
- tumor necrosis factor receptor superfamily member 1B
- tumor necrosis factor receptor superfamily, member 1B
- Tumor necrosis factor receptor type II
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