Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB, IHC, MA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
7088 |
| Alternate Names |
- E(Sp1) homolog
- enhancer of split groucho 1
- ESG
- ESG1Enhancer of split groucho-like protein 1
- GRG1
- transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
- transducin-like enhancer of split 1, homolog of Drosophila E(sp1)
- transducin-like enhancer protein 1
|
Research Areas for TLE1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
